Abstract: Mass lose, bending strength and surface coarseness of epoxy resin 648 and TDE-85 with different irradiation dosages are studied by simulating proton irradiation conditions of space environment on the ground, that is proton energy Ep=150 keV, beam density A=2.0×10¹² cm^-2s^-1, irradiation dosage range Φ=(0~5.0)×10¹⁶ cm^-2, vacuum degree 10^-6 Pa, and environment temperature 120 K. The test results show that with the increase of irradiation dosage, mass lose tends to increase sharply at first and then to grow gently, bending strength of epoxy resin 648 decreases monotonically, bending strength of TDE-85 increases firstly and then decreases, the resin surface shows carbonization effects and surface coarseness changes to some extents.