Abstract: In order to solve the problem of intensive power and time consumption during running test before satellites were transported to the launch site, dynamic characteristics of satellites in the process of road transportation was studied in this paper. The simulation analysis input spectrum was established by processing a large number of measured data. The Patran/Nastran finite element software was used to establish the co-simulation model of the packing box and satellite. Modal analysis and random vibration response analysis were carried out by the modal test of the assembly. The first six modal shapes, as well as the acceleration and stress response RMS values of the key parts of the model were obtained. The results indicate that the stress RMS value of each part of the co-simulation model is much lower than the material yield limit, and the satellite structure has enough safety margin. This method may accurately and effectively analyze the mechanical environment encountered by satellites in the process of road transportation, and provide a basis for the design of satellite structure and packing box.