Abstract: The spacecraft payload equipment for processing weak electromagnetic signals is vulnerable to the noise emitted by the electronic equipment of the platform, and such equipment includes the data management unit, the attitude control unit, and the power distribution block. In this paper, the related mechanism of interference is identified, and several anti-interference protection techniques are discussed, such as the overall shielding for the low frequency cables, the slot shielding for cables routing through panels, the shielding for the bracket outside the satellite, and the physical metal isolation for the external structure. These techniques have their engineering values, and can be used by spacecraft system engineers in the EMC design.