Abstract: In the Wenchang launching site located in Hainan province, the high humidity, high salt fog conditions, mould, and long distance transportation from Tianjin to Hainan pose challenges to the protection of the electronic equipment used in manned spacecraft. This paper firstly analyzes the influence of damp heat, salt fog and mould on the electronic equipment, and then proposes universal measures of the protection to reduce the adverse effects of environmental factors effectively.