Abstract: The hybrid FE-SEA method is widely applied for the mid-frequency mechanical environment predication of spacecraft. But the predication precision of the vibro-acoustic response mainly depends on the SEA parameters, such as the modal density, the damping loss factor and the coupling loss factor. The lack of SEA parameters will make the structure and load design of spacecraft difficult. In this paper, the method for acquiring the SEA parameters is applied. The SEA parameters for several typical structures under different boundary conditions are obtained by tests, which provide plenty of data for the parameter library, as well as provide data for the precise vibro-acoustic response predication of the structure.