Abstract: In order to improve the management of common quality problems in the spacecraft AIT process, a process quality management method based on 5M1E(Man, Machine, Material, Method, Measure and Environment) is proposed, which adopts an identification mode of top down and bottom up, and the planning as a whole and the classification are used to analyze and solve the common quality problems. Combined with the actual work, a case is considered to indicate that the 5M1E method is effective for the management of common quality problems.