Abstract: In the overall control of a small satellite, including the interface logic control between the satellite and the ground or between different units of the satellite, the safety control is an important issue. This paper discusses the related safety control measures, such as through power supply and grounding, cable examination, power scaling, input signal leveling, as well as key process establishment and implementation. It is shown that these measures can effectively ensure the safety of personnel, satellite products and MGSE, which helps to improve the checkout test quality.