Abstract: The energy deposition in layered-target irradiated by electron beam is closely related with the thermal and mechanical effects in the targets. In this paper, with the modified program SANDYL based on the Monte Carlo method, the energy deposition profiles in C-ph/Al/C-ph/Al and Al/Au/Al/Au under the pulsed electron beam irradiation with different incident energies are obtained. Based on the results, the energy deposition law in layered-target is analyzed and it is concluded that the peak value and its position are closely related with the incident energy of the electrons, and the energy deposition profiles are discontinuous at the interfaces of different layers.